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Pasireotide drastically inhibited GLP-1 secretion induced by Gs-coupled receptor stimulation through SSTR5-Gi-dependent inhibition of cAMP levels, suggesting that the main pathway was completely blocked

This particular molecule has been synthesized to stop or limit the action of the NNMT enzyme (N-methyltransferase), which is involved in a series of biochemical reactions in the body, one of its main functions related to the metabolism of nicotinamide (a form of vitamin B3)